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miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma
Despite significant development of melanoma therapies, death rates remain high. MicroRNAs, controlling posttranscriptionally gene expression, play role in development of resistance to BRAF inhibitors. The aim of the study was to assess the role of miR-410-3p in response to vemurafenib–BRAF inhibitor...
Autores principales: | Grzywa, Tomasz M., Klicka, Klaudia, Paskal, Wiktor, Dudkiewicz, Julia, Wejman, Jarosław, Pyzlak, Michał, Włodarski, Paweł K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299409/ https://www.ncbi.nlm.nih.gov/pubmed/32555626 http://dx.doi.org/10.1371/journal.pone.0234707 |
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