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Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity

Expression of CHST15 (carbohydrate sulfotransferase 15; chondroitin 4-sulfate-6-sulfotransferase; BRAG), the sulfotransferase enzyme that adds 6-sulfate to chondroitin 4-sulfate (C4S) to make chondroitin 4,6-disulfate (chondroitin sulfate E, CSE), was increased in malignant prostate epithelium obtai...

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Detalles Bibliográficos
Autores principales: Bhattacharyya, Sumit, Feferman, Leo, Han, Xiaorui, Xia, Ke, Zhang, Fuming, Linhardt, Robert J., Tobacman, Joanne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299535/
https://www.ncbi.nlm.nih.gov/pubmed/32595831
http://dx.doi.org/10.18632/oncotarget.27634