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The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade

AIMS: ST-elevation myocardial infarction is associated with high levels of cardiac sympathetic drive and release of the co-transmitter neuropeptide Y (NPY). We hypothesized that despite beta-blockade, NPY promotes arrhythmogenesis via ventricular myocyte receptors. METHODS AND RESULTS: In 78 patient...

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Detalles Bibliográficos
Autores principales: Kalla, Manish, Hao, Guoliang, Tapoulal, Nidi, Tomek, Jakub, Liu, Kun, Woodward, Lavinia, Dall’Armellina, Erica, Banning, Adrian P, Choudhury, Robin P, Neubauer, Stefan, Kharbanda, Rajesh K, Channon, Keith M, Ajijola, Olujimi A, Shivkumar, Kalyanam, Paterson, David J, Herring, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299634/
https://www.ncbi.nlm.nih.gov/pubmed/31834357
http://dx.doi.org/10.1093/eurheartj/ehz852