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HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen‐glucose deprivation injuries via H3K14 and H4K5 acetylation‐mediated BDNF expression

Vascular dementia (VaD) is the second most common cause of dementia, but the treatment is still lacking. Although many studies have reported that histone deacetylase inhibitors (HDACis) confer protective effects against ischemic and hypoxic injuries, their role in VaD is still uncertain. Previous st...

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Detalles Bibliográficos
Autores principales: Fang, Yao‐Ching, Chan, Lung, Liou, Jing‐Ping, Tu, Yong‐Kwang, Lai, Mei‐Jung, Chen, Chin‐I, Vidyanti, Amelia Nur, Lee, Hsueh‐Yun, Hu, Chaur‐Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299713/
https://www.ncbi.nlm.nih.gov/pubmed/32374084
http://dx.doi.org/10.1111/jcmm.15358