ATPR triggers acute myeloid leukaemia cells differentiation and cycle arrest via the RARα/LDHB/ERK‐glycolysis signalling axis

Acute myeloid leukaemia (AML) remains a therapeutic challenge and improvements in chemotherapy are needed. 4‐Amino‐2‐trifluoromethyl‐phenyl retinate (ATPR), a novel all‐trans retinoic acid (ATRA) derivative designed and synthesized by our team, has been proven to show superior anticancer effect comp...

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Detalles Bibliográficos
Autores principales: Du, Yan, Zhang, Mei‐ju, Li, Lan‐lan, Xu, Xiao‐Lin, Chen, Hao, Feng, Yu‐bin, Li, Yan, Peng, Xiao‐qin, Chen, Fei‐hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299716/
https://www.ncbi.nlm.nih.gov/pubmed/32391634
http://dx.doi.org/10.1111/jcmm.15353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299716/
https://www.ncbi.nlm.nih.gov/pubmed/32391634
http://dx.doi.org/10.1111/jcmm.15353

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