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Smad3 gene C‐terminal phosphorylation site mutation aggravates CCl(4)‐induced inflammation in mice

The expression of C‐terminal phosphorylated Smad3 (pSmad3C) is down‐regulated with the progression of liver disease. Thus, we hypothesized that pSmad3C expression may be negatively related to liver disease. To develop novel therapeutic strategies, a suitable animal model is required that will allow...

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Detalles Bibliográficos
Autores principales: Ding, Hanyan, Fang, Meng, Gong, Yongfang, Li, Dong, Zhang, Chong, Wen, Guanghua, Wu, Chao, Yang, Jingjing, Yang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299733/
https://www.ncbi.nlm.nih.gov/pubmed/32406200
http://dx.doi.org/10.1111/jcmm.15385