The inotropic agent digitoxin strengthens desmosomal adhesion in cardiac myocytes in an ERK1/2-dependent manner

Desmosomal proteins are components of the intercalated disc and mediate cardiac myocyte adhesion. Enhancement of cardiac myocyte cohesion, referred to as “positive adhesiotropy”, was demonstrated to be a function of sympathetic signaling and to be relevant for a sufficient inotropic response. We use...

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Detalles Bibliográficos
Autores principales: Schinner, Camilla, Olivares-Florez, Silvana, Schlipp, Angela, Trenz, Sebastian, Feinendegen, Manouk, Flaswinkel, Heinrich, Kempf, Ellen, Egu, Desalegn Tadesse, Yeruva, Sunil, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299919/
https://www.ncbi.nlm.nih.gov/pubmed/32556797
http://dx.doi.org/10.1007/s00395-020-0805-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299919/
https://www.ncbi.nlm.nih.gov/pubmed/32556797
http://dx.doi.org/10.1007/s00395-020-0805-3

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