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Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

The clinical diagnosis of synucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), is challenging, especially at an early disease stage, due to the heterogeneous and often non-specific clinical manifestations. The discovery of reliabl...

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Detalles Bibliográficos
Autores principales: Rossi, Marcello, Candelise, Niccolò, Baiardi, Simone, Capellari, Sabina, Giannini, Giulia, Orrù, Christina D., Antelmi, Elena, Mammana, Angela, Hughson, Andrew G., Calandra-Buonaura, Giovanna, Ladogana, Anna, Plazzi, Giuseppe, Cortelli, Pietro, Caughey, Byron, Parchi, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299922/
https://www.ncbi.nlm.nih.gov/pubmed/32342188
http://dx.doi.org/10.1007/s00401-020-02160-8