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Genomic deregulation of PRMT5 supports growth and stress tolerance in chronic lymphocytic leukemia

Patients suffering from chronic lymphocytic leukemia (CLL) display highly diverse clinical courses ranging from indolent cases to aggressive disease, with genetic and epigenetic features resembling this diversity. Here, we developed a comprehensive approach combining a variety of molecular and clini...

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Detalles Bibliográficos
Autores principales: Schnormeier, Ann-Kathrin, Pommerenke, Claudia, Kaufmann, Maren, Drexler, Hans G., Koeppel, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299935/
https://www.ncbi.nlm.nih.gov/pubmed/32555249
http://dx.doi.org/10.1038/s41598-020-66224-1