Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling

Elevated intraocular pressure (IOP) is a major risk factor for the development and progression of primary open angle glaucoma and is due to trabecular meshwork (TM) damage, which leads to impaired aqueous humor outflow. Here, we explore a novel molecular mechanism involved in glaucomatous TM damage....

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Detalles Bibliográficos
Autores principales: Roberts, Amanda L., Mavlyutov, Timur A., Perlmutter, Tanisha E., Curry, Stacy M., Harris, Sherri L., Chauhan, Anil K., McDowell, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299944/
https://www.ncbi.nlm.nih.gov/pubmed/32555351
http://dx.doi.org/10.1038/s41598-020-66756-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299944/
https://www.ncbi.nlm.nih.gov/pubmed/32555351
http://dx.doi.org/10.1038/s41598-020-66756-6

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