Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting

New bicyclic guanidine alkaloid, urupocidin C (Ur-C) along with the previously known urupocidin A (Ur-A) were isolated from the rare deep-sea marine sponge Monanchora pulchra, harvested in Northwestern Pacific waters. The unique structure of Ur-C was elucidated using 1D and 2D NMR spectroscopy as we...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Kudryashova, Ekaterina K., Kaune, Moritz, Makarieva, Tatyana N., Shubina, Larisa K., Busenbender, Tobias, Denisenko, Vladimir A., Popov, Roman S., Hauschild, Jessica, Fedorov, Sergey N., Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299949/
https://www.ncbi.nlm.nih.gov/pubmed/32555282
http://dx.doi.org/10.1038/s41598-020-66428-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299949/
https://www.ncbi.nlm.nih.gov/pubmed/32555282
http://dx.doi.org/10.1038/s41598-020-66428-5

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