Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

The function of Latexin (LXN) in inflammation has attracted attention. However, no data are available regarding its role in colitis. We report that LXN is a suppressor of colitis. LXN deficiency leads to the severity of colitis in DSS-induced mice, and LXN is required for the therapeutic effect of r...

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Detalles Bibliográficos
Autores principales: Li, Yaping, Huang, Baohua, Yang, Hua, Kan, Shuang, Yao, Yanling, Liu, Xin, Pu, Shiming, He, Guozhang, Khan, Taj-Malook, Qi, Guangying, Zhou, Zuping, Shu, Wei, Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299958/
https://www.ncbi.nlm.nih.gov/pubmed/32555320
http://dx.doi.org/10.1038/s41598-020-66789-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299958/
https://www.ncbi.nlm.nih.gov/pubmed/32555320
http://dx.doi.org/10.1038/s41598-020-66789-x

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