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Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

The function of Latexin (LXN) in inflammation has attracted attention. However, no data are available regarding its role in colitis. We report that LXN is a suppressor of colitis. LXN deficiency leads to the severity of colitis in DSS-induced mice, and LXN is required for the therapeutic effect of r...

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Detalles Bibliográficos
Autores principales:	Li, Yaping, Huang, Baohua, Yang, Hua, Kan, Shuang, Yao, Yanling, Liu, Xin, Pu, Shiming, He, Guozhang, Khan, Taj-Malook, Qi, Guangying, Zhou, Zuping, Shu, Wei, Chen, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299958/ https://www.ncbi.nlm.nih.gov/pubmed/32555320 http://dx.doi.org/10.1038/s41598-020-66789-x

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