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Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction

The blood-brain barrier (BBB) is a dynamic component of the brain-vascular interface that maintains brain homeostasis and regulates solute permeability into brain tissue. The expression of tight junction proteins between adjacent endothelial cells and the presence of efflux proteins prevents entry o...

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Detalles Bibliográficos
Autores principales: Nzou, Goodwell, Wicks, Robert T., VanOstrand, Nicole R., Mekky, Gehad A., Seale, Stephanie A., EL-Taibany, Aya, Wicks, Elizabeth E., Nechtman, Carl M., Marotte, Eric J., Makani, Vishruti S., Murphy, Sean V., Seeds, M. C., Jackson, John D., Atala, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299970/
https://www.ncbi.nlm.nih.gov/pubmed/32555384
http://dx.doi.org/10.1038/s41598-020-66487-8