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Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

New therapeutics targeting immune checkpoint proteins have significantly advanced treatment of non-small cell lung cancer (NSCLC), but protein level quantitation of drug targets presents a critical problem. We used multiplexed, targeted mass spectrometry (MS) to quantify immunotherapy target protein...

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Detalles Bibliográficos
Autores principales: Liebler, Daniel C., Holzer, Timothy R., Haragan, Alexander, Morrison, Ryan D., O’Neill Reising, Leslie, Ackermann, Bradley L., Fill, Jeff A., Schade, Andrew E., Gruver, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300007/
https://www.ncbi.nlm.nih.gov/pubmed/32555523
http://dx.doi.org/10.1038/s41598-020-66902-0