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SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth

Few studies have investigated the role of extracellular-matrix proteoglycans in the pathogenesis of drug-induced gingival overgrowth (DIGO). SPOCK1 is an extracellular proteoglycan that induces epithelial to mesenchymal transition (EMT) in several cancer cell lines and exhibits protease-inhibitory a...

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Detalles Bibliográficos
Autores principales: Alshargabi, Rehab, Sano, Tomomi, Yamashita, Akiko, Takano, Aiko, Sanada, Taiki, Iwashita, Misaki, Shinjo, Takanori, Fukuda, Takao, Sanui, Terukazu, Kishida, Shosei, Nishimura, Fusanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300011/
https://www.ncbi.nlm.nih.gov/pubmed/32555336
http://dx.doi.org/10.1038/s41598-020-66660-z