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Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution

Porcine coronavirus SADS-CoV has been identified from suckling piglets with severe diarrhea in southern China in 2017. The SADS-CoV genome shares ~95% identity to that of bat α-coronavirus HKU2, suggesting that SADS-CoV may have emerged from a natural reservoir in bats. Here we report the cryo-EM st...

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Detalles Bibliográficos
Autores principales: Yu, Jinfang, Qiao, Shuyuan, Guo, Runyu, Wang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300015/
https://www.ncbi.nlm.nih.gov/pubmed/32555182
http://dx.doi.org/10.1038/s41467-020-16876-4