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CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration

Detalles Bibliográficos
Autores principales: Krishnan, Gopinath, Zhang, Yu, Gu, Yuanzheng, Kankel, Mark W., Gao, Fen-Biao, Almeida, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300081/
https://www.ncbi.nlm.nih.gov/pubmed/32266467
http://dx.doi.org/10.1007/s00401-020-02154-6