Developmental Immaturity of Siglec Receptor Expression on Neonatal Alveolar Macrophages Predisposes to Severe Group B Streptococcal Infection

Streptococcus agalactiae (Group B Streptococcus, GBS) is the most common neonatal pathogen. However, the cellular and molecular mechanisms for neonatal susceptibility to GBS pneumonia and sepsis are incompletely understood. Here we optimized a mouse model of GBS pneumonia to test the role of alveola...

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Detalles Bibliográficos
Autores principales: Lund, Sean J., Patras, Kathryn A., Kimmey, Jacqueline M., Yamamura, Asami, Butcher, Lindsay D., Del Rosario, Pamela G.B., Hernandez, Gilberto E., McCoy, Alyssa M., Lakhdari, Omar, Nizet, Victor, Prince, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300150/
https://www.ncbi.nlm.nih.gov/pubmed/32535023
http://dx.doi.org/10.1016/j.isci.2020.101207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300150/
https://www.ncbi.nlm.nih.gov/pubmed/32535023
http://dx.doi.org/10.1016/j.isci.2020.101207

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