Development of a DNA double-strand break-free base editing tool in Corynebacterium glutamicum for genome editing and metabolic engineering

As a traditional amino acid producing bacterium, Corynebacterium glutamicum is a platform strain for production of various fine chemicals. Based on the CRISPR (Clustered regularly interspaced short palindromic repeats)-Cas9 system, gene editing tools that enable base conversion in the genome of C. g...

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Detalles Bibliográficos
Autores principales: Deng, Chen, Lv, Xueqin, Li, Jianghua, Liu, Yanfeng, Du, Guocheng, Liu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Special issue on Model chassis cells edited by Long Liu and Rodrigo Ledesma- Amaro
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300154/
https://www.ncbi.nlm.nih.gov/pubmed/32577397
http://dx.doi.org/10.1016/j.mec.2020.e00135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300154/
https://www.ncbi.nlm.nih.gov/pubmed/32577397
http://dx.doi.org/10.1016/j.mec.2020.e00135

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