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The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells

Ghrelin regulates both energy intake and glucose homeostasis. In the endocrine pancreas, ghrelin inhibits insulin release to prevent hypoglycemia during fasting. The mechanism through which this is accomplished is unclear, but recent studies suggest that ghrelin acts on δ cells to stimulate somatost...

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Detalles Bibliográficos
Autores principales: Yin, Terry C., Bauchle, Casey J., Rouault, Alix A.J., Stephens, Samuel B., Sebag, Julien A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300157/
https://www.ncbi.nlm.nih.gov/pubmed/32535024
http://dx.doi.org/10.1016/j.isci.2020.101216