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The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells
Ghrelin regulates both energy intake and glucose homeostasis. In the endocrine pancreas, ghrelin inhibits insulin release to prevent hypoglycemia during fasting. The mechanism through which this is accomplished is unclear, but recent studies suggest that ghrelin acts on δ cells to stimulate somatost...
Autores principales: | Yin, Terry C., Bauchle, Casey J., Rouault, Alix A.J., Stephens, Samuel B., Sebag, Julien A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300157/ https://www.ncbi.nlm.nih.gov/pubmed/32535024 http://dx.doi.org/10.1016/j.isci.2020.101216 |
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