Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach

The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a prolonged QT interval. Therefore, QT prolonga...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wang, Cao, Lu, Yuan, Yan, Yan, Leng, Dongjing, Tian, Shanshan, Zheng, Dongjie, Wang, Zhiguo, Bai, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300225/
https://www.ncbi.nlm.nih.gov/pubmed/32595491
http://dx.doi.org/10.3389/fphar.2020.00614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300225/
https://www.ncbi.nlm.nih.gov/pubmed/32595491
http://dx.doi.org/10.3389/fphar.2020.00614

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