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Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach

The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a prolonged QT interval. Therefore, QT prolonga...

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Detalles Bibliográficos
Autores principales:	Wang, Hui, Wang, Cao, Lu, Yuan, Yan, Yan, Leng, Dongjing, Tian, Shanshan, Zheng, Dongjie, Wang, Zhiguo, Bai, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300225/ https://www.ncbi.nlm.nih.gov/pubmed/32595491 http://dx.doi.org/10.3389/fphar.2020.00614

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