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Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach
The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a prolonged QT interval. Therefore, QT prolonga...
Autores principales: | Wang, Hui, Wang, Cao, Lu, Yuan, Yan, Yan, Leng, Dongjing, Tian, Shanshan, Zheng, Dongjie, Wang, Zhiguo, Bai, Yunlong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300225/ https://www.ncbi.nlm.nih.gov/pubmed/32595491 http://dx.doi.org/10.3389/fphar.2020.00614 |
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