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Weights for ordinal analyses of the modified Rankin Scale in stroke trials: A population-based cohort study

BACKGROUND: Ordinal/shift analyses of ordered measures like the modified Rankin Scale(mRS) are underused as primary trial outcomes for neurological disorders – despite statistical advantages – potentially hindered by poor clinical interpretability versus dichotomies, and by valuing state-transitions...

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Detalles Bibliográficos
Autores principales: Ganesh, Aravind, Luengo-Fernandez, Ramon, Pendlebury, Sarah T., Rothwell, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300241/
https://www.ncbi.nlm.nih.gov/pubmed/32577611
http://dx.doi.org/10.1016/j.eclinm.2020.100415