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Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma

Gastric carcinoma is the third major cause of cancer‐related death in China. Bcl‐2 and other BH3 family proteins are critically important in the process of apoptosis pathway, which may be a promising target. APG‐1252‐M1 specifically connects to Bcl‐2 and Bcl‐xl. The antitumor effect of APG‐1252‐M1 i...

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Detalles Bibliográficos
Autores principales: Yi, Hanjie, Qiu, Miao‐Zhen, Yuan, Luping, Luo, Qiuyun, Pan, Wentao, Zhou, Suna, Zhang, Lin, Yan, Xianglei, Yang, Da‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300393/
https://www.ncbi.nlm.nih.gov/pubmed/32346976
http://dx.doi.org/10.1002/cam4.3090