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SNGH16 regulates cell autophagy to promote Sorafenib Resistance through suppressing miR‐23b‐3p via sponging EGR1 in hepatocellular carcinoma

OBJECTIVE: Tumor cells could acquire drug resistance through cell autophagy. This study aimed to explore the role of SNHG16 in sorafenib‐resistant HCC cells and its mechanism with miR‐23b‐3p. METHODS: The sorafenib‐resistant Hep3B cell model was established. The SNHG16 and miR‐23b‐3p gene expression...

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Detalles Bibliográficos
Autores principales: Jing, Zhao, Ye, Xiaoping, Ma, Xiaojie, Hu, Xiangrong, Yang, Wenjun, Shi, Junping, Chen, Gongying, Gong, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300419/
https://www.ncbi.nlm.nih.gov/pubmed/32324343
http://dx.doi.org/10.1002/cam4.3020