TDP-43 Is Efficiently Transferred Between Neuron-Like Cells in a Manner Enhanced by Preservation of Its N-Terminus but Independent of Extracellular Vesicles

The misfolding of transactive response DNA-binding protein (TDP-43) is a major contributor to the pathogenesis of TDP-43 proteinopathies, including amyotrophic lateral sclerosis and frontotemporal lobar degeneration with TDP-43 inclusions, but also plays a role in other neurodegenerative diseases in...

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Detalles Bibliográficos
Autores principales: Sackmann, Christopher, Sackmann, Valerie, Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301158/
https://www.ncbi.nlm.nih.gov/pubmed/32595443
http://dx.doi.org/10.3389/fnins.2020.00540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301158/
https://www.ncbi.nlm.nih.gov/pubmed/32595443
http://dx.doi.org/10.3389/fnins.2020.00540

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