Proteomic Profile of Mouse Brain Aging Contributions to Mitochondrial Dysfunction, DNA Oxidative Damage, Loss of Neurotrophic Factor, and Synaptic and Ribosomal Proteins

The deleterious effects of aging on the brain remain to be fully elucidated. In the present study, proteomic changes of young (4-month) and aged (16-month) B6129SF2/J male mouse hippocampus and cerebral cortex were investigated by using nano liquid chromatography tandem mass spectrometry (NanoLC-ESI...

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Detalles Bibliográficos
Autores principales: Li, Yingchao, Yu, Haitao, Chen, Chongyang, Li, Shupeng, Zhang, Zaijun, Xu, Hua, Zhu, Feiqi, Liu, Jianjun, Spencer, Peter S., Dai, Zhongliang, Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301248/
https://www.ncbi.nlm.nih.gov/pubmed/32587661
http://dx.doi.org/10.1155/2020/5408452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301248/
https://www.ncbi.nlm.nih.gov/pubmed/32587661
http://dx.doi.org/10.1155/2020/5408452

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