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Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster

BACKGROUND: Scaffold proteins support a variety of key processes during animal development. Mutant mouse for the MAGUK protein Discs large 5 (Dlg5) presents a general growth impairment and moderate morphogenetic defects. RESULTS: Here, we generated null mutants for Drosophila Dlg5 and show that it o...

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Detalles Bibliográficos
Autores principales: Venugopal, Parvathy, Veyssière, Hugo, Couderc, Jean-Louis, Richard, Graziella, Vachias, Caroline, Mirouse, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301484/
https://www.ncbi.nlm.nih.gov/pubmed/32552730
http://dx.doi.org/10.1186/s12861-020-00218-0