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Stakeholder perspectives on adaptive clinical trials: a scoping review

BACKGROUND: Adaptive clinical trials (ACTs) represent an emerging approach to trial design where accumulating data are used to make decisions about future conduct. Adaptations can include comparisons of multiple dose tiers, response-adaptive randomization, sample size re-estimation, and efficacy/fut...

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Detalles Bibliográficos
Autores principales: Madani Kia, Tina, Marshall, John C., Murthy, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301522/
https://www.ncbi.nlm.nih.gov/pubmed/32552852
http://dx.doi.org/10.1186/s13063-020-04466-0