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Mesenchymal stem cells transfected with sFgl2 inhibit the acute rejection of heart transplantation in mice by regulating macrophage activation

BACKGROUND: Mesenchymal stem cells (MSCs) have become a promising candidate for cell-based immune therapy for acute rejection (AR) after heart transplantation due to possessing immunomodulatory properties. In this study, we evaluated the efficacy of soluble fibronectin-like protein 2 (sFgl2) overexp...

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Detalles Bibliográficos
Autores principales: Gao, Chao, Wang, Xiaodong, Lu, Jian, Li, Zhilin, Jia, Haowen, Chen, Minghao, Chang, Yuchen, Liu, Yanhong, Li, Peiyuan, Zhang, Baotong, Du, Xuezhi, Qi, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301524/
https://www.ncbi.nlm.nih.gov/pubmed/32552823
http://dx.doi.org/10.1186/s13287-020-01752-1