Immune Network Modeling Predicts Specific Nasopharyngeal and Peripheral Immune Dysregulation in Otitis-Prone Children

Acute otitis media (AOM) pathogenesis involves nasopharyngeal colonization by potential otopathogens and a viral co-infection. Stringently-defined otitis prone (sOP) children show characteristic patterns of immune dysfunction. We hypothesized that otitis proneness is largely a result of altered sign...

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Detalles Bibliográficos
Autores principales: Morris, Matthew C., Chapman, Timothy J., Pichichero, Michael E., Broderick, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301607/
https://www.ncbi.nlm.nih.gov/pubmed/32595639
http://dx.doi.org/10.3389/fimmu.2020.01168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301607/
https://www.ncbi.nlm.nih.gov/pubmed/32595639
http://dx.doi.org/10.3389/fimmu.2020.01168

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