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Protective effect of hypoxia inducible factor-1α gene therapy using recombinant adenovirus in cerebral ischaemia-reperfusion injuries in rats

CONTEXT: Hypoxia-inducible factor-1α (HIF-1α)-induced genes can improve blood circulation. OBJECTIVE: To investigate brain protective effect of recombinant adenovirus-mediated HIF-1α (AdHIF-1α) expression and its mechanism. MATERIALS AND METHODS: Male SD rats were used to establish focal cerebral is...

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Detalles Bibliográficos
Autores principales: Li, Ya-Qi, Hui, Zhi-Rong, Tao, Tao, Shao, Kang-Yu, Liu, Zhi, Li, Min, Gu, Li-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301712/
https://www.ncbi.nlm.nih.gov/pubmed/32432963
http://dx.doi.org/10.1080/13880209.2020.1762667