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Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes

BACKGROUND: Angiostrongylus cantonensis is an important food-borne zoonotic parasite. Humans are non-permissive hosts, and this parasite develops into fifth-stage larvae (L5) in the brain and subarachnoid cavity and then induces eosinophilic meningitis and eosinophilic meningoencephalitis. Excretory...

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Detalles Bibliográficos
Autores principales: Chen, Kuang-Yao, Chen, Yi-Ju, Cheng, Chien-Ju, Jhan, Kai-Yuan, Wang, Lian-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301976/
https://www.ncbi.nlm.nih.gov/pubmed/32552877
http://dx.doi.org/10.1186/s13071-020-04189-w