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Epigenetic silencing of AATK in acinar to ductal metaplasia in murine model of pancreatic cancer
BACKGROUND: Cancer subtype switching, which involves unclear cancer cell origin, cell fate decision, and transdifferentiation of cells within a confined tumor microenvironment, remains a major problem in pancreatic cancer (PDA). RESULTS: By analyzing PDA subtypes in The Cancer Genome Atlas, we ident...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301993/ https://www.ncbi.nlm.nih.gov/pubmed/32552862 http://dx.doi.org/10.1186/s13148-020-00878-6 |