Improving Precision and Power in Randomized Trials for COVID-19 Treatments Using Covariate Adjustment, for Binary, Ordinal, and Time-to-Event Outcomes

Time is of the essence in evaluating potential drugs and biologics for the treatment and prevention of COVID-19. There are currently over 400 clinical trials (phase 2 and 3) of treatments for COVID-19 registered on clinicaltrials.gov. Covariate adjustment is a statistical analysis method with potent...

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Detalles Bibliográficos
Autores principales: Benkeser, David, Díaz, Iván, Luedtke, Alex, Segal, Jodi, Scharfstein, Daniel, Rosenblum, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302221/
https://www.ncbi.nlm.nih.gov/pubmed/32577668
http://dx.doi.org/10.1101/2020.04.19.20069922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302221/
https://www.ncbi.nlm.nih.gov/pubmed/32577668
http://dx.doi.org/10.1101/2020.04.19.20069922

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