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A novel chalcone derivative suppresses melanoma cell growth through targeting Fyn/Stat3 pathway
BACKGROUND: Fyn has been documented to have oncogenic features in multiple tumors, which might be a potential therapeutic target, however, few studies on the function role of Fyn and its specific inhibitors in melanoma. METHODS: We investigated the impacts of Fyn and its inhibitor Lj-1-60 on melanom...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302361/ https://www.ncbi.nlm.nih.gov/pubmed/32565740 http://dx.doi.org/10.1186/s12935-020-01336-2 |