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A novel chalcone derivative suppresses melanoma cell growth through targeting Fyn/Stat3 pathway

BACKGROUND: Fyn has been documented to have oncogenic features in multiple tumors, which might be a potential therapeutic target, however, few studies on the function role of Fyn and its specific inhibitors in melanoma. METHODS: We investigated the impacts of Fyn and its inhibitor Lj-1-60 on melanom...

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Detalles Bibliográficos
Autores principales:	Tang, Ling, Long, Jing, Li, Keke, Zhang, Xu, Chen, Xiang, Peng, Cong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302361/ https://www.ncbi.nlm.nih.gov/pubmed/32565740 http://dx.doi.org/10.1186/s12935-020-01336-2

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