Cargando…

RelB regulates the homeostatic proliferation but not the function of Tregs

BACKGROUND: RelB, a member of the NF-κB family, plays a critical role in the development of T cells. However, the role of RelB in Foxp3(+) regulatory T cells (Tregs) remains controversial. RESULTS: Using a bone marrow chimeric mouse model, we demonstrated that the expansion of Foxp3(+) Tregs in vivo...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Shuping, Wu, Weiwei, Wang, Zhaoxia, Wang, Zhaopeng, Su, Qinghong, Li, Xiaofan, Yu, Yong, Zhang, Weidong, Zhu, Mingzhao, Lin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302365/
https://www.ncbi.nlm.nih.gov/pubmed/32552667
http://dx.doi.org/10.1186/s12865-020-00366-9