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RelB regulates the homeostatic proliferation but not the function of Tregs
BACKGROUND: RelB, a member of the NF-κB family, plays a critical role in the development of T cells. However, the role of RelB in Foxp3(+) regulatory T cells (Tregs) remains controversial. RESULTS: Using a bone marrow chimeric mouse model, we demonstrated that the expansion of Foxp3(+) Tregs in vivo...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302365/ https://www.ncbi.nlm.nih.gov/pubmed/32552667 http://dx.doi.org/10.1186/s12865-020-00366-9 |