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Preparation of a phosphotyrosine-protein standard for use in semiquantitative western blotting with enhanced chemiluminescence
Protein tyrosine phosphorylation is key to activation of receptor tyrosine kinases (RTK) that drive development of some cancers. One challenge of RTK-targeted therapy is identification of those tumors that express non-mutated but activated RTKs. Phosphotyrosine (pTyr) RTK levels should be more predi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302481/ https://www.ncbi.nlm.nih.gov/pubmed/32555693 http://dx.doi.org/10.1371/journal.pone.0234645 |