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Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

OBJECTIVES: Malaria, caused by Plasmodium infection, remains a major global health problem. Monocytes are integral to the immune response, yet their transcriptional and functional responses in primary Plasmodium falciparum infection and in clinical malaria are poorly understood. METHODS: The transcr...

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Detalles Bibliográficos
Autores principales: Loughland, Jessica R, Woodberry, Tonia, Field, Matt, Andrew, Dean W, SheelaNair, Arya, Dooley, Nicholas L, Piera, Kim A, Amante, Fiona H, Kenangalem, Enny, Price, Ric N, Engwerda, Christian R, Anstey, Nicholas M, McCarthy, James S, Boyle, Michelle J, Minigo, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302943/
https://www.ncbi.nlm.nih.gov/pubmed/32566226
http://dx.doi.org/10.1002/cti2.1144