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Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain
A decrease in adult hippocampal neurogenesis has been linked to age-related cognitive impairment. However, the mechanisms involved in this age-related reduction remain elusive. Glucocorticoid hormones (GC) are important regulators of neural stem/precursor cells (NSPC) proliferation. GC are released...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303016/ https://www.ncbi.nlm.nih.gov/pubmed/31222184 http://dx.doi.org/10.1038/s41380-019-0440-2 |