Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain

A decrease in adult hippocampal neurogenesis has been linked to age-related cognitive impairment. However, the mechanisms involved in this age-related reduction remain elusive. Glucocorticoid hormones (GC) are important regulators of neural stem/precursor cells (NSPC) proliferation. GC are released...

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Detalles Bibliográficos
Autores principales: Schouten, M., Bielefeld, P., Garcia-Corzo, L., Passchier, E. M. J., Gradari, S., Jungenitz, T., Pons-Espinal, M., Gebara, E., Martín-Suárez, S., Lucassen, P. J., De Vries, H. E., Trejo, J. L., Schwarzacher, S. W., De Pietri Tonelli, D., Toni, N., Mira, H., Encinas, J. M., Fitzsimons, C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303016/
https://www.ncbi.nlm.nih.gov/pubmed/31222184
http://dx.doi.org/10.1038/s41380-019-0440-2

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