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Alternaria toxins as casein kinase 2 inhibitors and possible consequences for estrogenicity: a hybrid in silico/in vitro study

Emerging mycotoxins produced by Alternaria spp. were previously reported to exert cytotoxic, genotoxic, but also estrogenic effects in human cells. The involved mechanisms are very complex and not fully elucidated yet. Thus, we followed an in silico target fishing approach to extend knowledge on the...

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Detalles Bibliográficos
Autores principales: Aichinger, Georg, Dellafiora, Luca, Pantazi, Foteini, Del Favero, Giorgia, Galaverna, Gianni, Dall’Asta, Chiara, Marko, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303061/
https://www.ncbi.nlm.nih.gov/pubmed/32328700
http://dx.doi.org/10.1007/s00204-020-02746-x