RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses

Keratoconus is a highly prevalent (1 in 2000), genetically complex and multifactorial, degenerative disease of the cornea whose pathogenesis and underlying transcriptomic changes are poorly understood. To identify disease-specific changes and gene expression networks, we performed next generation RN...

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Detalles Bibliográficos
Autores principales: Shinde, Vishal, Hu, Nan, Mahale, Alka, Maiti, George, Daoud, Yassine, Eberhart, Charles G., Maktabi, Azza, Jun, Albert S., Al-Swailem, Samar A., Chakravarti, Shukti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303170/
https://www.ncbi.nlm.nih.gov/pubmed/32555404
http://dx.doi.org/10.1038/s41598-020-66735-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303170/
https://www.ncbi.nlm.nih.gov/pubmed/32555404
http://dx.doi.org/10.1038/s41598-020-66735-x

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