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Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1

The gut–brain axis is currently being studied as a therapeutic strategy for neurological diseases, especially Alzheimer’s disease (AD). Obesity results in the gut microbiota dysbiosis, which includes butyrate-producing bacteria are reduced. Although sodium butyrate (NaB) has emerged as the potential...

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Detalles Bibliográficos
Autores principales: Kim, Seo Yihl, Chae, Chang Woo, Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Kim, Jun Sung, Lim, Jae Ryong, Lee, Joo Eun, Cho, Ji Hyeon, Park, Hansoo, Park, Changho, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303181/
https://www.ncbi.nlm.nih.gov/pubmed/32555166
http://dx.doi.org/10.1038/s41419-020-2663-1