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Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1
The gut–brain axis is currently being studied as a therapeutic strategy for neurological diseases, especially Alzheimer’s disease (AD). Obesity results in the gut microbiota dysbiosis, which includes butyrate-producing bacteria are reduced. Although sodium butyrate (NaB) has emerged as the potential...
Autores principales: | Kim, Seo Yihl, Chae, Chang Woo, Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Kim, Jun Sung, Lim, Jae Ryong, Lee, Joo Eun, Cho, Ji Hyeon, Park, Hansoo, Park, Changho, Han, Ho Jae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303181/ https://www.ncbi.nlm.nih.gov/pubmed/32555166 http://dx.doi.org/10.1038/s41419-020-2663-1 |
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