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Genetic variants associated with alcohol dependence co-ordinate regulation of ADH genes in gastrointestinal and adipose tissues

GWAS studies have identified genetic variants associated with Alcohol Dependence (AD), but how they link to genes, their regulation and disease traits, remains largely unexplored. Here we integrated information on the 3D genome organization with expression quantitative loci (eQTLs) analysis, using C...

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Detalles Bibliográficos
Autores principales: Hibberd, Rebecca, Golovina, Evgeniia, Farrow, Sophie, O’Sullivan, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303195/
https://www.ncbi.nlm.nih.gov/pubmed/32555468
http://dx.doi.org/10.1038/s41598-020-66048-z